MOLECULAR AND BIOLOGICAL MECHANISMS OF DEVELOPMENT OF OSTEOPOROSIS AFTER CHOLECYSTECTOMY
Abstract
Osteoporosis is a global problem faced by millions of people around the world. One of the main causes of osteoporosis is a lack of vitamin D, which can be acquired as a result of cholecystectomy. This review includes an analysis of the literature on the composition and functions of bile, bile acids and micelle formation. With the coordinated work of these components, adequate absorption of fats and fat-soluble vitamins (in particular vitamin D) occurs. However, if one of these components fails (for example, after cholecystectomy), the entire mechanism of absorption suffers, which can lead to a lack of vitamin D, and, as a consequence, to osteoporosis
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